| Sunday, September 13, 2020 | ||
| Barcelona | 00:00 | Elche |
| Real Madrid | 00:00 | Getafe |
| Sunday, September 20, 2020 | ||
| Levante | 00:00 | Atlético de Madrid |
| Sevilla | 00:00 | Elche |
| Sunday, October 25, 2020 | ||
| Real Valladolid | 14:00 | Deportivo Alavés |
| Cádiz | 16:00 | Villarreal |
| Getafe | 18:30 | Granada |
| Real Sociedad | 21:00 | Huesca |
| Monday, October 26, 2020 | ||
| Levante | 21:00 | Celta Vigo |
| Friday, October 30, 2020 | ||
| Eibar | 21:00 | Cádiz |
| Saturday, October 31, 2020 | ||
| Real Madrid | 14:00 | Huesca |
| Athletic Bilbao | 16:00 | Sevilla |
| Osasuna | 18:30 | Atlético de Madrid |
| Deportivo Alavés | 21:00 | Barcelona |
| Sunday, November 1, 2020 | ||
| Real Betis | 14:00 | Elche |
| Celta Vigo | 16:00 | Real Sociedad |
| Granada | 18:30 | Levante |
| Valencia | 21:00 | Getafe |
| Monday, November 2, 2020 | ||
| Villarreal | 21:00 | Real Valladolid |
| Friday, November 6, 2020 | ||
| Elche | 21:00 | Celta Vigo |
| Saturday, September 12, 2020 | ||
| Burnley | 01:00 |  Manchester United |
Manchester City  | 01:00 |  Aston Villa |
| Sunday, October 25, 2020 | ||
Southampton  | 16:00 |  Everton |
| Wolverhampton Wanderers | 18:30 |  Newcastle United |
Arsenal  | 21:15 |  Leicester City |
| Monday, October 26, 2020 | ||
| Brighton & Hov… | 19:30 |  West Bromwich Albion |
| Burnley | 22:00 |  Tottenham Hotspur |
| Friday, October 30, 2020 | ||
| Wolverhampton Wanderers | 22:00 |  Crystal Palace |
| Saturday, October 31, 2020 | ||
| Sheffield United | 14:30 | Manchester City |
| Burnley | 17:00 |  Chelsea |
Liverpool  | 19:30 |  West Ham United |
| Sunday, November 1, 2020 | ||
| Aston Villa | 14:00 | Southampton |
| Newcastle United | 16:00 | Everton |
| Manchester United | 18:30 | Arsenal |
| Tottenham Hotspur | 21:15 | Brighton & Hov… |
| Monday, November 2, 2020 | ||
| Fulham | 19:30 | West Bromwich Albion |
| Leeds United | 22:00 | Leicester City |
| Friday, November 6, 2020 | ||
| Southampton | 22:00 | Newcastle United |